[6] Her parents were devout Jains, but they enrolled Sheth in the local Catholic school,[4] which she attended until age 12 when her family moved to Trenton.

She spent a summer abroad in Amsterdam as part of the intensive International Theatre Workshop, studying under acting teachers such as Kristin Linklater.

Brooks conducted an extensive international search for the ideal actor to portray Maya, and says of Sheth, "Once I came across her, I watched everything that I could.

[20] Following her success in Looking for Comedy in the Muslim World, Sheth appeared in the recurring role of Martina in the NBC TV series The Singles Table, starring opposite Alicia Silverstone and John Cho.

[21] She also performed in the ensemble The Trouble With Romance and starred in the thriller First Fear opposite Sean Patrick Flanery.

Sheth starred opposite Lisa Ray in two lesbian themed films, I Can't Think Straight and The World Unseen, both written and directed by Sarif.

Sheth went on to perform in Why Am I Doing This and starred in Stalemate opposite Josh Randall and Burgess Jenkins, for which she was nominated for Best Actress at the 2011 Staten Island Film Festival.

She guest starred in the popular television shows Nip/Tuck, Royal Pains, and NCIS: Los Angeles, and provided the voices for Sumi and Shark in the animated feature film Johnny Bravo Goes to Bollywood, based on Cartoon Network's popular animated television series Johnny Bravo.

In 2011, Sheth starred opposite Mercedes Masöhn and Angela Zahra in Three Veils, which portrays three Middle Eastern women living in the United States.

[23] Sheth embarked on her acting career at a time when opportunities for South Asians, particularly Indian American women, in the industry were scarce.

Beyond her acting, Sheth actively supports underrepresented groups, including Asian Americans, by participating in festivals, workshops, and panels.

[24] Sheth was selected as the spokesperson for CHI haircare products and represented Reebok's New York sneaker in their 2008 international Freestyle campaign.

"[27] While at New York University, Sheth was selected to be a part of AmeriCorps, a division of the Corporation for National and Community Service created by U.S. President Bill Clinton.

Through AmeriCorps, she worked at an inner-city high school, developing progressive lesson plans and activities, tutoring, and dealing with conflict resolution.