Twenty-seven-year-old Sherlock Holmes (Igor Petrenko) meets with Dr. John Watson (Andrei Panin) - a veteran Army doctor who has just returned from the war in Afghanistan.
They both live in cramped rented rooms in central London at a boarding house run by Mrs Hudson (Ingeborga Dapkūnaitė).
His violin playing sounds terrible, and he is neither a martial arts expert nor a crack shot Dr Watson makes him out to be.
The genius investigator and the Doctor confront extraordinary villains: Professor Moriarty (Alexei Gorbunov), charming Pesutova Baba (Lyanka Gryu), and others.
She has taken a liking to Watson, but has a problem with Holmes who has no clear occupation and disturbs other tenants with his violin playing and science experiments.
Dr. Watson shortly gets involved in his new friend's life full of exciting and dangerous adventures and becomes his loyal sidekick.
Alone without friends and family he starts looking for a flat, but he soon meets a stranger, a young man who seems to disturb the work of the local policemen from Scotland Yard as well as their chief, Inspector Lestrade.
The young man describes himself as a private detective named Sherlock Holmes, together he and Watson decide to share a flat at 221B Baker Street.
Four women have been murdered and while the police arrest a suspect and prepare to bring him to court, Holmes and Watson work around the clock to prevent his death.
He is scared and on the verge of a nervous breakdown due to the fact that he is 33 years old which means he needs to pass a mystical rite of passage after which he would become the full owner of the entire heritage of the Musgrave family.
On the same day, a remarkable incident occurs at the National Bank when a man named Ebenezer Buckley comes to trade a suitcase of banknotes for pure gold.
Holmes makes the assumption that there is a direct link between the redheaded Lord and Mr. Buckley's death, and that the happenings are only part of a bigger, cunning plan of someone who wants to undermine the economy of the British Kingdom.
During a Christmas party taking place in the estate of Count Brachear, the organiser is killed under unknown circumstances.
Watson is extremely surprised when Holmes manipulates the evidence and sets Inspector Lestrade on the wrong track.
Three years after Holmes's death, Dr. Watson is married to Mrs Hudson and his stories about the famous detective have been successfully reissued.
So when the doctor is approached by a young girl with a request to find out the reason for the death of her lover, Watson tries to solve the case.