She recorded four top-10 finishes including her maiden win at the season-ending Symetra Tour Championship.

[5] In 2016, Santiwiwatthanaphong mainly played on the Symetra Tour which she made 17 cuts from 19 starts with seven top-ten finishes.

She claimed her second Symetra Tour title at the Island Resort Championship and finished sixth on the money list to earn LPGA membership for the 2017 season.

In 2018, Santiwiwatthanaphong made ten cuts from 21 starts on the LPGA Tour, including her career-best at the Kingsmill Championship that she finished tied for seventh.

[7] In 2019, Santiwiwatthanaphong played 18 tournaments on the LPGA Tour and made three cuts.