The college was affiliated to the University of Delhi by a special act of the Indian parliament.

The 3rd king of Bhutan, Jigme Dorji Wangchuck laid the foundation stone for Sherubtse School in June 1966.

In June 2003, the school was combined with 9 other institutes of higher learning to form the Royal University of Bhutan.

The departments of business and economics are to be transferred to the Royal Institute of Management (RIM) over the next several years.

In "Beyond the Sky and Earth," Jamie Zeppa provides a detailed account of her experiences teaching at Sherubtse College.