Shi Wuzi (史務滋) (died January 2, 691[1]) was a Chinese politician of the Chinese Tang dynasty and Wu Zetian's Zhou dynasty, serving briefly as chancellor during Wu Zetian's reign.
It is not known when Shi Wuzi was born, but it is known that he was from Liyang (溧陽, in modern Changzhou, Jiangsu).
As of 690, when Wu Zetian had just taken over the throne from her son Emperor Ruizong, establishing Zhou and interrupting Tang, Shi was serving as the minister of vassal affairs (司賓卿, Sibin Qin), when she promoted him to be Nayan (納言), the head of the examination bureau of government (鸞臺, Luantai) -- a post considered one for a chancellor.
Wu Zetian put Shi and her secret police official Lai Junchen in charge of the investigations.
Afterwards, Lai Junchen reported to Wu Zetian that Shi was trying to absolve the Lius.