[2] S. dysenteriae has the ability to invade and replicate in various species of epithelial cells and enterocytes.

[3] The most commonly observed signs associated with Shigella dysentery include colitis, malnutrition, rectal prolapse, tenesmus, reactive arthritis, and central nervous system problems.

Further, S. dysenteriae is associated with the development of hemolytic-uremic syndrome, which includes anemia, thrombocytopenia, and kidney failure.

[3] Shigella infections may be contracted by a lack of monitoring of water and food quality, unsanitary cooking conditions and improper hygiene practices.

When acting as a neurotoxin, severe cases of shigellosis are developed, inducing comas and meningismus.