The Shire of Nebo was a local government area in Central Queensland, Queensland, Australia, about 80 kilometres (50 mi) south-west of the regional city of Mackay.

The Shire, administered from the town of Nebo, covered an area of 10,034.6 square kilometres (3,874.4 sq mi), and existed as a local government entity from 1883 until 2008, when it was amalgamated with the Shires of Belyando and Broadsound to form the Isaac Region.

Traditionally a rural area, producing beef, sugar, sorghum and other grains, coal mining is now a major employer, with eight coal mines in the area and capacity for a further five.

The area was first explored by Europeans when Ludwig Leichhardt came in 1845, and was named Nebo by William Landsborough in 1856.

[6][7] On 15 March 2008, under the Local Government (Reform Implementation) Act 2007 passed by the Parliament of Queensland on 10 August 2007, Nebo merged with the Shires of Belyando and Broadsound to form the Isaac Region.