She has made several notable appearances including the televised Live from Disney World Night of Joy, the Gospel According to VH1, and a White House performance for President George Bush.

In 2016, Caesar was honored with a star on Hollywood Walk of Fame, for her contributions in gospel music.

Her professional music career began in 1958 at 19, when she approached Albertina Walker about joining The Caravans, one of the most popular gospel groups at that time.

Albertina wanted the vocally talented young Caesar in her group after hearing her sing a solo.

Caesar recorded and performed with Albertina Walker, Cassietta George, Inez Andrews, Delores Washington, Josephine Howard, Eddie Williams, and James Herndon while in the Caravans.

Her first LP on the Hob label was entitled I'll Go, backed up by the Institutional Radio Choir and includes the classics "Oh Peter, Don't Be Afraid" and "Choose Ye This Day".

Other hits soon followed, with recordings such as "Satan, We're Gonna Tear Your Kingdom Down", "God's Not Dead, He's Yet Alive" and the classic "Don't Drive Your Mama Away".

Caesar searched for a gospel label and decided to sign with Word Records in 1980 and went on to win several more Grammy Awards during the next several years and beyond.

She stayed with Word for many years and recorded some of the biggest hits of her career such as "God's Got It All in Control", "Hold My Mule" (which later went viral as a Thanksgiving-related Internet meme under the title "You Name It"),[7] "He's Working It Out for You", "Jesus, I Love Calling Your Name" and "You're Next in Line for a Miracle".

She received two Black Gospel Song of the Year Awards for "He's Working It Out for You" and "Hold My Mule".

She acted in movies, such as Why Do Fools Fall in Love (1998) with Larenz Tate and Little Richard, Fighting Temptations (2003) with Beyoncé and Cuba Gooding Jr., and The Unseen (2005) with Steve Harris.

[10] In 2016, she found herself back at the very top of the gospel Billboard chart with her CD release Fill This House.

She had first enrolled at North Carolina State College in 1956 to study business education, but left two years later to pursue her music career.

[1] She returned to school and graduated with honors from Shaw University with a Bachelor of Science degree in Business Administration in 1984.

The couple were co-pastors of the 1,500-member Mount Calvary Word of Faith Church in Raleigh, North Carolina until his death on July 4, 2014.