Shiselweni is a region of Eswatini, located in the south of the country.

It borders Lubombo in the northeast and Manzini Region in the northwest.

These are local administration centres, and also parliamentary constituencies.

Each inkhundla is headed by an indvuna yenkhundla or governor with the help of bucopho.

The present tinkhundla are: Christianity and Islam are the main religions in the region.