Trams run through Shudehill to Bury, Altrincham, Manchester Airport, Piccadilly and Victoria.

The bus station, designed by Jefferson Sheard Architects, replaced the former Cannon Street bus station, under the Manchester Arndale; since the redevelopment of Manchester city centre, the latter has disappeared along with Cannon Street itself.

Bus services are operated under the Bee Network by Stagecoach Manchester and Go North West.

[5] There are frequent buses to destinations in the north and the west of Greater Manchester, including Bury, Middleton, Rochdale, Salford, Eccles, Bolton and the Trafford Centre.

In April 2009, the Manchester Megabus stop moved from the Chorlton Street coach station to Shudehill Interchange.