Si Prachan (Thai: ศรีประจันต์, pronounced [sǐː prā.t͡ɕān]) is a district (amphoe) in the eastern part of Suphan Buri province, central Thailand.

[2] Neighbouring districts are (from the south clockwise): Mueang Suphan Buri, Don Chedi and Sam Chuk; and Sawaeng Ha, Pho Thong, Samko and Wiset Chai Chan of Ang Thong province.

The main water resource of the district is the Tha Chin River.

Si Prachan is divided into nine subdistricts (tambons), which are further subdivided into 64 administrative villages (mubans).

This Suphan Buri Province location article is a stub.