Sicyos macrophyllus is a rare species of flowering plant in the Cucurbitaceae, the squash family.

[1] Common names include alpine bur cucumber,[2] largeleaf bur-cucumber, and 'anunu.

[3] This is a perennial herb producing vines up to 15 meters long and 4 centimeters thick.

It is not a federally listed endangered or threatened species, but the United States government made it a candidate for protection in 1990.

Feral pigs, sheep, and cattle destroy native plants and cause erosion of the hilly habitat.

They are also vectors for the seeds of introduced species of plants, including several types of noxious weed.