[1] Along with Anita Kaul Basu, he is a founder-director of Tree of Knowledge Digital, a greenfield venture in the area of interactive edutainment events, e-learning, gaming, publishing, and select television production.

After a hiatus of many years, he returned to the stage in Prime Time's landmark production of Mahesh Dattani’s Dance Like a Man, playing the roles of Jayaraj and Amritlal.

Siddhartha Basu's career in television began in 1977 as a documentary filmmaker with a company called TVNF after he completed his MA in English Literature from University of Delhi.

Promoted by Siddhartha and Anita Kaul Basu, and Karun Prabhakaran, BIG Synergy built its reputation as a leader in the field of factual entertainment, starting off as one of the country's first independent television production houses.

The second edition of the show KBC2 began airing in August 2005 and notched up the highest-ever opening in the history of Indian television, going on to sustain its position among the most-watched programs in the country.

Starting in 2017, Tree of Knowledge has produced 4 seasons of NewsWiz, a quiz show based on news and current affairs, with participation by high school students from all over the country, hosted by Rajdeep Sardesai, on India Today TV.

Siddhartha is married to Anita Kaul, who worked as a journalist with India Today magazine from 1983 to 1988 and with whom in 1988 he set up Synergy, a television production company.