Flanigan received widespread acclaim and a collective 45 nominations for her performance, including the Critics' Choice Movie Award for Best Actress and the Independent Spirit Award for Best Female Lead opposite fellow nominees Frances McDormand, Viola Davis, Carey Mulligan, and Zendaya.

[7] In an interview with Playboy, writer Ryan Gajewski described Flanigan as, "A new kind of movie star in a variety of ways."

Flanigan initially met Hittman when she and director Scott Cummings were filming the documentary Buffalo Juggalos.

[8] In December 2020, it was announced that Flanigan would star in Matthew Kaundart's psychological drama My Twin Is Dead.

[10] She is also set to lead the indie thriller Only the Good Survive, from writer-director Dutch Southern, which recently premiered at South by Southwest and the musical Eco Village, an official selection of the Rotterdam International Film Festival.