The siege of Mequinenza (15 May to 8 June 1810) saw a 16,000-man Imperial French corps commanded by Louis Gabriel Suchet invest a 1,000-strong Spanish garrison under Colonel Carbon.

Mequinenza is located at the confluence of the Ebro and Segre Rivers about 211 kilometres (131 mi) west of Barcelona.

Once the road was ready, the French dragged their siege cannons to the top and opened fire on the castle.

Since Mequinenza was at the head of navigation on the Ebro, Suchet was able to use the town as a supply base in his subsequent operations during the siege of Tortosa in the winter of 1810 and 1811.

The powerful fortress of Jaca meekly surrendered to Mortier on 21 March 1809 and the towns of Monzón and Fraga were soon occupied.