Sierra Sciences, LLC is a biotechnology company founded by William H. Andrews, former director of molecular biology at Geron Corporation.

[5][6] For this discovery, Andrews was awarded second place as "National Inventor of the Year" in 1997 by the Intellectual Property Owners Association.

In 1997, Andrews left Geron, and, in 1999, founded Sierra Sciences to pursue the anti-aging implications of these discoveries, intending to find a drug that would "switch on" this repressed gene.

In 2002, Richard Offerdahl, co-founder of Zycad Corporation and former director of Digi International, assumed the position of Chairman of the Board of Sierra Sciences.

[11] Sierra Sciences discovered methods of assaying TERT promoter modulatory agents, allowing the company to efficiently check a variety of compounds to see if they inhibit repression of hTERT, in 2005.