It is located south of the Moncayo Massif between the valleys of the Jalón and the Aranda rivers, rising north of the N-234 road, roughly between Calatayud and Torrelapaja.

[1] These mountains are mostly covered with low maquis shrub and they have been repopulated with pine since the 20th century.

The Sierra de la Virgen is often subject to wildfires in periods of prolonged drought.

Native trees include juniper and Carrasca (Quercus ilex),[2] among others.

There are other smaller mountain chains named "Sierra de la Virgen" in Spain.