Sietze de Vries' father was the organist at the Gereformeerde Kerk (Vrijgemaakt) in Niezijl, where his grandfather was the sexton.
de Vries studied at the Groningen Conservatory with Johan Beeftink, Jan Jongepier and Wim van Beek until he obtained his bachelor's degree in 1994.
[1] At the Royal Conservatory of The Hague followed two years in the organ class of Jos van der Kooy, graduating with a master's degree in 1996.
Since 2017, he has shared with Stef Tuinstra the organist position of the Martinikerk Groningen, which was held by Wim van Beek for 60 years before them.
De Vries is the artistic director of the Stichting Hinszorgel Leens, a foundation that promotes young talent.
The organ there by Marten Eertman from 1907 (originally I/p/10)[8] is being rebuilt in several stages into a two-manual instrument with independent pedal in the style of the late baroque (II/P/21).