Growing up in Utrecht, the Netherlands, as the child of an American father and a Dutch mother, Signe Tollefsen started to sing at the age of 7.

She composed her first songs on guitar at the age of 14, inspired by artists such as Janis Joplin, Edith Piaf, and Paul Simon.

Between 2006 and 2009, she shared the stage with Ane Brun, Stephen Malkmus, Alela Diane, Luka Bloom, and Japan's singer David Sylvian.

In 2008 famous Dutch singer Mathilde Santing recorded her song "Sweet Tears" on her album Forty-Nine.

In March 2011 she was a guest musician in De Wereld Draait Door, a popular Dutch TV show with an average of 1.5 million viewers, singing "Borrowed Song", which will appear on her second album.