Jibladze and Ninoshvili organized a one-week strike in support of school inspector Liadze, who was dismissed from his job due to his liberal leanings.
Having recovered, Jibladze returned to Guria, where he re-established a relationship with Egnate Ninoshvili, became friends with Isidore Ramishvili and Arsen Tsitlidze.
Jibladze started working in the "Phylloxera Committee", which represented the body for the fight against phylloxera and where Egnate Ninoshvili, Nikolay Chkheidze and young people expelled from schools were employed, using the activities of the committee and frequent trips to the provinces to educate the peasants and spread revolutionary propaganda.
In December 1892, he attended the meeting in Zestaponi, after which he actively participated in the work of Mesame Dasi, the "third group" of Georgian nationalists, liberals and socialists.
He practically became the leader of Mesame Dasi in Georgia, worked for its organizational formation, and in 1898 even formed the Tbilisi Social-Democratic Committee, of which he was the chairman.
In 1900, he went to Saint Petersburg to establish a connection with the Russian Social Democratic Labour Party center, where he was helped by Isidore Kvitsaridze, who lived there.
Nonetheless as the movement gathered strength the RSDLP took on an important role in leading it, while still maintaining the internal debate that soon produced, on a larger stage, the split between the Bolsheviks and the Mensheviks.
After the split in the RSDLP, he was still publishing anti-Bolshevik letters from Siberia, and after the amnesty speech, he joined Zhordania in the fight against Bolshevik influences in the party.
In January 1906, Arsena Georgiashvili, directed by Jibladze, killed the Deputy Crown Prince of the Caucasus, General Fyodor Griaznov.
On 10 April 1921 he presided over a conference that adopted a seven-point resolution and proposed the government of the Georgian SSR to hold a referendum, in which case they promised that the Menshevik party would limit itself to open criticism and cooperation.
Faced with the Bolshevik regime's refusal to compromise and repressions, Jibladze started to create a united front of resistance.
Jibladze was the initiator of Catholicos-Patriarch Ambrosius's appeal to the Genoa Conference, in which he requested the liberation of Georgia from Soviet occupation.
The Cheka discovered his location, kidnapped his body and buried it in the Russian cemetery of Vera under secret circumstances.