With López Moreira, the office of First Lady was reopened in Paraguay after a vacant period, since the previous President, Horacio Cartes, ordered its closure due to being divorced.

[2] López Moreira's maternal grandfather is businessman Nicolás Bó, who amassed his fortune during the regime of the late Paraguayan dictator Alfredo Stroessner, and owned media companies and various other businesses.

[2] López Moreira's first marriage was to wealthy cattle rancher José Félix Ugarte (circa 1990s), with whom she had three children, two sons and a daughter.

reported that on Paraguayan newspapers, ABC Color compared her to Jacqueline Kennedy Onassis and Michelle Obama, and Última Hora considered her appearance "impeccable", while ¡Hola!

[11] In July 2020, it was announced that López Moreira would debut as a television presenter in a television program aimed to support entrepreneurs during the COVID-19 pandemic in Paraguay, named Aikuaa ("To know" in Guarani language), to be broadcast on the state-run public broadcasting channel Paraguay TV, as well as on social media.