Based on the physical concept of "schools-within-a-school," Simi Valley High School was constructed with three instructional quads, each having an administrative area.

Currently, the school is configured with five major instructional areas, a multipurpose building, a gym and dressing room facilities, a library, a counseling facility, an administration building, a new area of portable classrooms, a stadium and athletic fields, a new senior patio, and a band room with all different types of instruments.

The school is a charter member of the Coastal Canyon League (CCL), a conference within the CIF Southern Section (CIF-SS) that was established in 2014.

[10] Prior to 2014, the school was a long-time member of the Marmonte League.

Simi Valley's primary rival is Royal High School on the west side of the city.