[3] Quadarella competed in the women's 1500 metre freestyle event at the 2017 World Aquatics Championships,[4][5] winning the bronze medal.

[7] In July 2021, at the 2020 Summer Olympics, which were also postponed to 2021 due to the pandemic, she won the bronze medal in the 800 metre freestyle with a time of 8:18.35.

[8] For the 1500 metre freestyle at the 2022 World Aquatics Championships, Quadarella placed fifth with a time of 16:03.84, finishing over 14 seconds behind bronze medalist Lani Pallister of Australia.

[11][12] At the 2022 European Aquatics Championships, held two months later in Rome, Quadarella won the gold medal in the 800 metre freestyle with a time of 8:20.54.

[20] The final day, she won the silver medal in the 400 metre freestyle, finishing behind gold medalist Isabel Marie Gose of Germany with a time of 4:04.77.