Simone Bonomi (born 8 November 1980) is an Italian former association footballer who played as a midfielder.
Bonomi started his career at AC Milan youth teams.
In 1999, he was signed by Serie C2 club Prato in co-ownership bid.
In January 2002, he joined Poggibonsi of Serie C2 on loan, and also played once in relegation playoff.
He never became a regular of the team, although made his Serie A debut on 25 October 2003 against US Lecce.