Simone Cantoni (Muggio, Switzerland, 1736- Gorgonzœla, Milan, Italy, 3 March 1818) was a Swiss architect of the Neoclassical period, active mainly in Northern Italy.
His father was his first mentor, but sent him as a young man to Rome to study classical architecture.
He gained a post in Lombardy directing the construction of the Palazzo Mellerio in central Milan.
After the fire in the Ducal Palace of Genoa in 1777, he restored the building by replacing the wooden ceiling.
He erected the Pertusati House in Milan using Palladian proportions.