He came to prominence as a member of industrial metal band Ministry and its side projects, and as a primary songwriter on their albums The Last Sucker and From Beer to Eternity.

In addition to his role in Ministry (co-writing credits on the abovementioned releases and guitar on 2008's Cover Up album) and primary writing credits for Revolting Cocks albums Sex-O Olympic-O and ¿Got Cock?, Quirin toured the U.S. and worked with DJ Hardware on the 2009 ReVamp tour.

He also worked on the project Supermanic – a Los Angeles-based rock band co-founded by Quirin and vocalist & music producer Kallaghan (Charles Massabo).

In addition to his work with Supermanic, in January 2014, Quirin announced his foray into the EDM world by releasing new industrial/aggrotech/electro dance tracks to fans.

[7] On May 15, 2021, Quirin announced his departure from Ministry, to work on other projects and look after his health, following years of accusations of underage sexual abuse.