It is the junction point of the P'yŏngŭi and Kaech'ŏn lines of the Korean State Railway.

After the bridge across the Yalu River was opened on 1 November 1911, connecting Sinŭiju to Dandong, China, Sinanju station became a stop for international trains to and from Manchuria.

During the Korean War, the station and the surrounding area – an important hub for land transport in the north – was bombed heavily.

In December 1952, the administrative districts of North Korea were reorganised, and Sinanju was incorporated into the city of Anju.

The station was rebuilt after the war by Youth Shock Troops, and was at the same time renamed to its current name.