Sipuel v. Board of Regents of the University of Oklahoma, 332 U.S. 631 (1948), is a per curiam United States Supreme Court decision involving racial segregation toward African Americans by the University of Oklahoma and the application of the Fourteenth Amendment to the United States Constitution.

[1] Ada Lois Sipuel (February 8, 1924 – October 18, 1995), born in Chickasha, Oklahoma, was the daughter of a minister.

[2] The petitioners, acting on behalf of Miss Sipuel, were Thurgood Marshall of New York City, and Amos Hall, of Tulsa (also on the brief Frank D. Reeves).

The court ruled that the state of Oklahoma must provide instruction for Blacks equal to that of Whites, requiring the admission of qualified black students to previously all-white state law schools, reversing the Supreme Court of Oklahoma decision.

In addition, Ada Sipuel was "not only an excellent student, but was welcomed by her classmates who did not agree with the exclusionary policy that the State had unsuccessfully tried to defend."