Siquisiquesuchus (meaning "Siquisique crocodile" after the town in Lara, Venezuela, near where the first described specimens were found) is an extinct genus of gavialid crocodilian.

It is known from cranial remains and a few postcranial bones found in Miocene-age rocks of the Castillo Formation in northwestern Venezuela.

[2] Siquisiquesuchus was found by Brochu and Rincón to be the oldest known gavialoid from South America, sharing various anatomical details with Gryposuchus colombianus (to which it is particularly similar) and other South American gavialoids.

[2] Later studies have concurred with a gavialoid identity, finding the genus to be related to such genera as Gavialis, Gryposuchus, Ikanogavialis, and Piscogavialis.

[4] Brochu and Rincón noted that Siquisiquesuchus was found in marginal marine deposits.