Sir Francis Drake Boulevard is an approximately 43.8 mile east–west arterial road in Marin County, California, running from the trailhead for Point Reyes Lighthouse at the end of the Point Reyes Peninsula to Interstate 580 just west of the Richmond-San Rafael Bridge.

It is a main thoroughfare through (from west to east) the communities of Inverness, Point Reyes Station, Olema, Lagunitas-Forest Knolls, San Geronimo, Woodacre, Fairfax, San Anselmo, Ross, Kentfield, Greenbrae, and Larkspur.

The road overlaps State Route 1 between Point Reyes Station and Olema.

It is named for the English privateer, explorer and world circumnavigator[1] Francis Drake, whose ship The Golden Hind landed somewhere along the Pacific coast of North America in 1579, claiming the area for England as "Nova Albion."

Facing public concern for Drake's reputed history in the slave trade, the Fairfax town council voted unanimously in early 2021 to change the road's name within the town's jurisdiction.