Major-General Sir Francis Wheler, 10th Baronet CB (1801–1878) was a British Indian Army officer, serving in the Bengal cavalry.

He inherited the baronetcy on the death of his older brother Sir Trevor on 6 September 1869.

Wheler married twice: 1) 1827 Caroline Palmer, with whom he had two children: 2) 1841 Elizabeth Bishop (ca.

1819–1900), daughter of William Bishop, of Grayswood, Surrey, with whom he had three children: Sir Francis died on 4 April 1878, aged 76.

Lady Wheler died at South Lawn, Hesketh-park, Southport, on 16 March 1900, aged 80.