Sir George Speke, 2nd Baronet (1 October 1653 – 14 January 1683) was an English politician who sat in the House of Commons between 1675 and 1683.
Speke was the son of Sir Hugh Speke, 1st Baronet of Hasilbury, Wiltshire and his wife Anne Croke, daughter of John Mayne or Mayney of Staplehurst, Kent.
[2] Speke died at the age of 29 and was buried in the church at Box, Wiltshire when the Baronetcy became extinct.
[1] Speke married Rachael Wyndham, daughter of Sir William Wyndham, 1st Baronet and his wife Frances Hungerford, daughter of Anthony Hungerford.
She later married Richard Musgrave, and died in or before December 1711.