[1] Hume was the son of Sir John Hume, 2nd Baronet and Sydney Hamilton, and in 1695 he succeeded to his father's baronetcy.
He was the Member of Parliament for County Fermanagh in the Irish House of Commons between 1713 and his death in 1731.
[2] In 1714 he was made a member of the Privy Council of Ireland.
From 1715 to 1727 he was a Groom of the Chamber to George I of Great Britain.
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