[3] Gigs held there included a number by The Golden Horde, Toasted Heretic, Sonic Youth with support band Nirvana, Therapy?, The Wedding Present and The Fall.

During late 1980s, the club ran a series of three-night long acid house weekenders, which attracted DJs such as Laurent Garnier,[4] Shades of Rhythm and Justin Robertson.

Artists that performed there over these years included Phil Lynott, John Martyn, ex-Clash Mick Jones' Big Audio Dynamite, The Pogues and The Sisters of Mercy.

Started in 1988 by Shane Johnson and Greg Dowling, this was to become one of the top clubs in Europe in the early 1990s,[12] supplemented with the addition of the Back Bar with DJ's such as Donkeyman (Mark Ring) and Stephen Grainger (Stevie G).

By the mid 1990s Sir Henry’s had become a house venue,[13] playing host to some of genre's better known artists such as Kerri Chandler, Roger Sanchez, Glenn Underground, Cajmere, Derrick May, Migs, Fred Everything, Charles Webster, Kevin McKay, and Mike Pickering.