Sir James Cunynghame, 2nd Baronet (c. 1685 – 1747) of Milncraig, Ayr and Livingstone, Linlithgow, was a Scottish politician who sat in the House of Commons from 1715 to 1722.
Cunynghame was the eldest son of Sir David Cunynghame, 1st Baronet of Milncraig and Livingstone and his first wife Isabella Dalrymple, daughter of James Dalrymple, 1st Viscount of Stair.
He succeeded his father in the baronetcy on 28 January 1708.
[1] Cunynghame was returned unopposed as Whig Member of Parliament for Linlithgowshire at the 1715 general election.
[2] He was succeeded in the baronetcy by his brother, David, a Lieutenant-General in the Army.