Sir John Tyrwhitt, 5th Baronet (c. 1663–1741), of Stainfield, Lincolnshire, was a British landowner and politician who sat in the House of Commons between 1715 and 1734.
Tyrwhitt was the only surviving son of Sir Philip Tyrwhitt, 4th Baronet MP of Stainfield, Lincolnshire and his wife Penelope de la Fountain, daughter of Sir Erasmus de la Fountain of Kirkby Beilars, Leicestershire.
His father died in July 1688, when he succeeded to the estates and baronetcy.
[1] Tyrwhitt was returned unopposed as Whig Member of Parliament for Lincoln on his family's interest at the 1715 general election.
He supported the Administration in 1716 on the septennial bill, but in 1719 opposed the repeal of the Occasional Conformity and Schism Acts.