Sir Thomas Cullum, 1st Baronet (1587 – 6 April 1664) was an English businessman and holder of civic offices including Sheriff of London.
As a younger son he was sent in 1607 to London and apprenticed to one John Rayney, a draper, and on the expiration of his apprenticeship was taken by his master into partnership.
Cullum by shrewdness and industry amassed a large fortune in his business in Gracechurch Street, and became an alderman and a member of the Drapers' Company.
Mary died in 1637, aged 35, and was buried at All Hallows Lombard Street, London.
At the Restoration Cullum was rewarded by being created a baronet on 18 June 1660, but he seems to have fallen into disfavour with the ruling powers, as on 17 July 1661 he had a pardon under the great seal for all treasons and rebellions, with all their concomitant enormities, committed by him before the 29th of the preceding December.