Sir Thomas Wynn, 1st Baronet (1677–1749) was a Welsh politician who sat in the House of Commons from 1713 to 1749.
Wynn was born in March 1677, the eldest son of Griffith Wynn of Bodvean and his wife Catherine Vaughan, daughter of William Vaughan of Corsygedol, Merioneth.
In 1712 he became the Sheriff of Caernarvonshire and at the 1713 general election he was returned unopposed as Member of Parliament for Caernarvon Boroughs.
In 1724 he became Clerk of the Household to the Prince of Wales and Constable of Caernarvon castle, Forester of Snowdon and Steward of Bardsey until 1727.
He also became Clerk of the Green Cloth in 1727 until his death and equerry to George II on his accession to the throne.