Sir William Robert Pryke, 1st Baronet (15 March 1847 – 30 March 1932) was a British businessman who was Lord Mayor of London from 1925 to 1926.
The son of Richard Reeve Pryke, of Bury St Edmunds, Pyke was educated at the City of London College, after which he entered the office of a broker.
As sheriff, he was knighted by the King on the occasion of his visit to the city on the reopening of Southwark Bridge in 1921.
On 3 November 1926, he was created a Baronet, of Wanstead in the County of Essex.
Pryke was also a member of the Lee Conservancy Board, of the Wanstead Urban District Council, and of the Essex County Council, which he chaired for nine years.