[citation needed] Haqqani is currently wanted by the FBI for questioning due to his role in the 2008 Kabul Serena Hotel attack that killed six people, including American citizen Thor David Hesla[7]and an attempted assassination of President Hamid Karzai, with the U.S. State Department designating him a Specially Designated Global Terrorist and offering a reward of $10 million for information about his location that will lead to his arrest.

Haqqani has admitted planning the January 14, 2008 attack against the Serena Hotel in Kabul that killed six people, including American citizen Thor David Hesla.

[25][26][13] On 31 May 2020, British Taliban expert Antonio Guistozzi told Foreign Policy that Sirajuddin Haqqani was infected with COVID-19, which resulted in him being absent from the group's leadership mix.

Speaking at a religious school in Khost Province, he said: "Monopolizing power and hurting the reputation of the entire system are not to our benefit... more responsibility has been placed on our shoulders and it requires patience and good behavior and engagement with the people."

[35] In June 2024, Haqqani made his first visit overseas since the takeover, to meet UAE President Mohamed bin Zayed Al Nahyan in Abu Dhabi.

[36] In 2010, Haqqani released a 144-page Pashto-language book, a training manual entitled Military Lessons for the Benefit of the Mujahedeen, where he appears more radical than the Talibans, as it shows influences from al-Qaida, supporting beheading and suicide bombings while legitimizing targeting the West, asking Muslims there to "blend in, shave, wear Western dress, be patient.

"[37] Writing in November 2011, an analyst said some 10,000 copies of the book were printed and distributed in Afghanistan and Pakistan in a single month, describing Haqqani's work as being "printed on high-quality paper, with black-and-white photos and solidly bound, the manual for guerrillas and terrorists opens with directions for how to set up a jihadi cell, how to obtain financing, how to recruit members, and how to train them", also containing details about deadly weapons, how to make and use explosive devices and which infrastructure to target, such as railroad tracks, bridges and more.

[38] When Akhtar Mansour was elected as the new leader of the Taliban in 2015, a communication was posted quoting Sirajuddin Haqqani: "My particular recommendation to all members of the Islamic Emirate is to maintain their internal unity and discipline.