Hasse was asked to reset the opera for the Elector of Saxony and this version was first performed on 3 August 1763 at the Opernhaus am Zwinger in Dresden.

[1] Siroe received its modern-day premiere in an uncut version by Ensemble Serse in September 2008 in a performance which, including two fifteen-minute intervals, lasted just under five hours.

Siroe was revived in an abridged form for the 2011 London Handel Festival by Ensemble Serse at St George's Hanover Square Church in London on 15 April 2011 in a performance which lasted two and a half hours.

[2][3] In 2018 the Nederlandse Reisopera staged performances in the Netherlands of a version lasting about 3 hours.

Siroe is in love with Emira, daughter of Cosroe's former enemy Asbite, disguised as a man called Idaspe, while Siroe is loved in turn by his father's mistress Laodice.