Sisters is a city in Deschutes County, Oregon, United States.

[6] According to the United States Census Bureau, the city has a total area of 1.87 square miles (4.84 km2), all land.

On Cascade Avenue, there is a lot of pedestrian traffic and many specialty stores and galleries.

East of Sisters the two highways split, with 126 heading to Redmond and 20 going to Bend.

This region experiences warm (but not hot) and dry summers, with no average monthly temperatures above 71.6 °F (22.0 °C).

29.0% of all households were made up of individuals, and 12.2% had someone living alone who was 65 years of age or older.

25.2% of all households were made up of individuals, and 8.8% had someone living alone who was 65 years of age or older.

The Sisters Ranger District Office is located at Pine Street and Highway 20.

[18] Hiking, biking and horse riding trails go from the city limits into the Three Sisters Wilderness.

[21][22] as is Big Lake Youth Camp operated by Seventh-day Adventists since 1963.