The Sixth Street Viaduct spans the Los Angeles River, the Santa Ana Freeway (US 101), and the Golden State Freeway (I-5), as well as Metrolink (Orange County and 91/Perris Valley lines), Amtrak (Pacific Surfliner and Southwest Chief), and Union Pacific (along with Metrolink's Riverside Line) railroad tracks and several local streets.

In 1986, the Caltrans bridge survey found the Sixth Street Viaduct eligible for inclusion in the National Register of Historic Places.

Prior to the demolition, Los Angeles mayor Eric Garcetti recorded the R&B song "101SlowJam", backed by musicians from the city's Roosevelt High School, and issued it via a video on his own YouTube channel.

[8] The newly completed bridge is designed by architect Michael Maltzan and the HNTB Design-Build team and contractors Skanska and Stacy and Witbeck.

When opened, the new span included single-direction bicycle lanes separated from motor traffic with rubber curb bumps and impact-forgiving bollards, a design feature that was universally panned as unsafe and dangerous to cyclists using the bridge.