Sizzano is a comune (municipality) in the Province of Novara in the Italian region Piedmont, located about 80 kilometres (50 mi) northeast of Turin and about 20 kilometres (12 mi) northwest of Novara.

As of 31 December 2004, it had a population of 1,452 and an area of 10.5 square kilometres (4.1 sq mi).

[3] Sizzano borders the following municipalities: Carpignano Sesia, Cavaglio d'Agogna, Fara Novarese, and Ghemme.

All grapes destined for DOC wine production need to be harvested to a yield no greater than 10 tonnes/ha.

The finished wine must attain a minimum alcohol level of 12% in order to be labelled with the Sizzano DOC designation.