Skullbone is an unincorporated community in Gibson County, Tennessee, United States.

It is located to the east of Bradford and is centered on Tennessee State Route 105.

[2] The name was changed to Skullbone officially on April 26, 1898, when a United States Post Office opened there.

The name has come into use as a reflection of local "bare-knuckle" fights held in the community, where strikes to the skull were common.

Hampton's Store, the only business currently operating in the community has elaborate murals painted on the side of the building depicting the Kingdom of Skullbonia's domain, bare-knuckle fighters, as well as declaring that there is a "Mayor's Office Upstairs," though it is unincorporated and has no elected council or mayor.