SkyGreece Airlines was founded in Athens, Greece in October 2012, by a group of Greek-Canadian entrepreneurs and a retired priest.

The company's main mission was to connect the Greek diaspora to their homeland by offering non-stop flights between Greece and North America year-round.

SkyGreece also inaugurated service to New York and Thessaloniki with several days postponed blaming the capital controls and the lack on money for the fuel.

In August 2015, a crack on the cockpit window caused the airplane to be grounded in Zagreb airport and the flight schedule to fall behind by several days.

On 3 September 2015, SkyGreece Airlines filed a notice of intention to make a proposal under the Bankruptcy and Insolvency Act in Canada.