Employing revolutionary new gravity-lock and laser-cable technology to traverse the ever-changing terrain of the High Frontier, Mike Summit's Sky Commanders and General Plague's Raiders are locked in mortal combat with the fate of the entire world hanging in the balance!"

The storyline of Sky Commanders comprises the daily adventures of a multi-national group of soldiers and mountaineering specialists from all over the world who battle the evil General Lucas Plague and his goon squad of villainous mercenaries and miscreants, "The Raiders", whose aim is to seize control of the planet.

The series is set on a new continent deep in the South Pacific, which was created by the emergence to the surface world of a new and powerful, unstable radioactive element, called "Theta Seven" (θ-7).

Travel throughout the new continent is only possible by means of high-altitude flight, or by using Laser Cables: a specialized version of a rappelling cord emitted from combat backpacks worn by both Raider and Sky Commander.

On August 28, 2012, Warner Archive released Sky Commanders: The Complete Series on DVD in region 1 as part of their Hanna-Barbera Classic Collection.