The second season of CSI: Crime Scene Investigation premiered on CBS on September 27, 2001, and ended May 16, 2002.

The series stars William Petersen and Marg Helgenberger.

The murder of a Police Chief leads Willows and Brown to Miami ("Cross Jurisdictions"), in the second season of CSI.

The Las Vegas CSIs investigate another series of gruesome, unprecedented, and unsolvable crimes, including the murder of the son of a Las Vegas mogul ("Burked"), the disappearance of a University student ("Chaos Theory"), the death of a construction worker ("Overload"), the discovery of a decomposed body in a bag ("Bully for You"), a scuba diver discovered up a tree in the desert ("Scuba Doobie-Doo"), a fetish murder ("Slaves of Las Vegas"), and a death at a spa ("Alter Boys").

Meanwhile, Catherine and Sara investigate both a suspected suicide-by-train ("Caged") and a homicide at a remote convenience store ("And Then There Were None"), Warrick is allowed to head the crime lab ("Ellie"), Grissom and Willows come to face to face with a serial killer in a courtroom ("Identity Crisis"), and Nick studies the death of a woman who drowned in the desert ("Anatomy of a Lye"), after finding himself the target of a stalker ("Stalker").