ET from Comcast, due to the small amount of time which passed between Charter's settlement of their new NBCUniversal carriage agreement and the channel's closure.

The network's last programming day consisted of a full-series marathon of Syfy's Continuum, a final sign of its later channel drift.

[5][13] The end of Cloo was coincidental with another Comcast announcement that the female-focused Oxygen would be switched to a true crime focus the same day within the coming months.

Programming initially included popular and cult television series such as Simon & Simon, Miami Vice, The A-Team, Dragnet (1967–70 version), Emergency!, Adam-12, Knight Rider, The Equalizer, Homicide: Life on the Street, JAG, Profiler, Magnum, P.I., The Rockford Files, The Burning Zone and more recent canceled series such as EZ Streets, Karen Sisco, and Deadline, Conviction, and Medical Investigation.

As Sleuth, it also aired mystery and suspense films such as Scarface, The Jackal, Casino, Sneakers and Mercury Rising.

On February 25, 2007, the channel aired a fourteen-hour movie marathon entitled "Chiller On Sleuth" to promote the launch of Chiller, a sister horror and suspense programming that launched four days later on March 1; The movies that aired during this marathon are Wait Until Dark, Psycho, I Saw What You Did (the 1988 version), and The Island.