He started playing guitar in his youth and he would become billed on radio as "The Boy With A Thousand Fingers" and by the 1930s became famous as member of The Georgia Wildcats, his crisp modern guitar-playing would be admired by virtuoso Les Paul.

[1] As a songwriter, he composed some 200 songs, but was best known for writing commercial radio jingles for large corporations, like US Steel, Alcoa, Westinghouse, Chevrolet and for Iron City Beer for the Pittsburgh Brewing Company.

Bryant by 1928, aged 20, had made his first recording "Ain't She Sweet", as a member of a stringed band called "The Harmony Boys".

Bryant then spend nine years with Georgian fiddler Clayton McMichen, a former member of the Skillitt-Lickers, as part of his group "The Georgia Wildcats", another popular and influential string band, the group originally based in Atlanta, left the city, and started performing on several radio stations throughout Cincinnati, Chicago, St. Louis, Louisville and others, most of the band had separated from McMichen and moved to Pittsburgh in 1940 where he and the Georgia Wildcats became regulars on radio KDKA's new early morning program Farm Hour, and there were very few Hillbilly performers heard as widely throughout the South-Eastern and Mid-Western States in the 1930s[citation needed].

With his back-up group, the Wildcats, he wrote and recorded such novelty songs during his career as "Eeny Meeny Dixie Deeny", the closest he ever came to having a hit on the Billboard charts.